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bp0007rdr4 | Developmental Processes in Ruminants | REDR2010

Developmental programming of the ovine placenta

Fowden AL , Ward JW , Wooding FBP , Forhead AJ

The pattern of intrauterine growth and size at birth, in particular, programmes the structure and function of tissues later in life in many species, which has important implications for the incidence of adult-onset generative diseases in human populations. In mammals, the main determinant of intrauterine growth is the placental supply of nutrients which, in turn, depends on the size, morphology, transport characteristics and endocrine function of the placenta. However, compare...